New C-3 Chiral Building Blocks : Chiral
introduce enantiomerically pure aziridine-2-carboxylates as new C-3 chiral
building blocks which easily lead to various optically pure nitrogen containing
molecules including natural and unnatural a-
and b-amino acid derivatives.
Some of our core aziridine derivatives (both enantiomers of aziridine-2-carboxylates,
aziridine-2-carboxamides, 2-hydroxymethylazirdines, 4-chloromethyl-1,3-oxazolidin-2-ones,
5-hydroxymethyl-1,3-oxazolidin-2-ones) are available from Sigma-Aldrich
as reagents to help your research.
of opposite isomers are also available from
2(R)-isomer of the aziridine-2-carboxylate in the same manner.
Novel Aziridine Chemistry I : Oxazolidinones
Various enantiomerically pure functionalized oxazolidinones
are available up to Kg scale using our own aziridine technology. Some
examples are shown below.
Ask oxazolidinone chemistry to us
Functionalized oxazolidin-2-ones are available
Novel Aziridine Chemistry II : 2,3-Diaminopropanoic
We offer 2-azido-3-aminopropanoates with +99% optical purity
and would be pleased to perform customized syntheses of these molecules
to help your process development and to provide you chiral building blocks
Following 2-azido-3-aminopropanoates are commercially available
We can offer you chiral diaminopropionates with two different
Novel Aziridine Chemistry III : Imidazolidinones
We provide uniquely functionalized chiral imidazolidinones
containing three randomization points with +99% optical purity
Active research is undergoing to provide the following functionalized
Novel Aziridine Chemistry IV : Sphingosines
Sphingosine is a well-known constituent of cell membranes
and the precursor of ceramides. All stereoisomers including their derivatives
and homologues are available with more than +99% of assay and optical
purity. We offer diverse sphingosines and ceramides for new drug or functional
Also all four stereoisomers of dihydrosphingosines and their corresponding
ceramides are available
All isomers with different chain length are also available.